Typical seed round size for biotech startups in Chicago

Based on 12 Form D filings by Chicago biotech issuers at seed stage, filed Oct 2024 – Aug 2026. Updated monthly. Change any segment to compare.

The numbers

  • Median seed raise: $1.2M
  • Middle half of rounds: $386k – $5.7M
  • Filings in sample: 12
  • Rounds under $1M: 50%
  • Rounds over $5M: 33%
  • Updated Aug 2026

Read this number carefully

Form D undercounts small SAFE rounds and rounds that rely on other exemptions. Treat the median as a ceiling for "typical", not a target.

Compare segments

Biotech · Seed · Boston ($4.2M)

Biotech · Seed · Bay Area ($3.8M)

Biotech · Seed · San Diego ($1.9M)

Biotech · Seed · New York ($2.5M)

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